Research

 

Jenn’s research focuses on how social and biological processes interact over the life course and how social factors “get under the skin” to impact health. She has studied how socioeconomic status shapes immune function and risk of infections as well as links between infections and chronic diseases of aging. On-going projects include understanding the social determinants of the human microbiome, the causes of stalling life expectancy in the US and UK, and the demography and epidemiology of COVID-19.

Schöley J, Aburto JM, Kashnitsky I, Kniffka MS, Zhang L, Jaadla H, Dowd JB, Kashyap R. (2022). Life expectancy changes since COVID-19. Nature Human Behaviour. Oct 17:1-1.

Aburto, JM, Tilstra AM, Floridi G and Dowd JB (2022). Significant impacts of the COVID-19 pandemic on race/ethnic differences in US mortality. Proceedings of the National Academy of Sciences Vol. 119 Issue 35

Dowd, JB., Rotondi V, Adriano L, Brazel DM, Block P, Ding X, Liu Y and Mills MC (2020). Demographic science aids in understanding the spread and fatality rates of COVID-19. Proceedings of the National Academy of Sciences:

Aburto JM, Schöley J, Zhang L, Kashnitsky I, Rahal C, Missov TI, Mills MC, Dowd JB, Kashyap R. (2021). Quantifying impacts of the COVID-19 pandemic through life expectancy losses. International Journal of Epidemiology.

Block, P, Hoffman M, Raabe IJ, Dowd JB, Rahal C, Kashyap R and Mills MC) (2020). Social network-based distancing strategies to flatten the COVID 19 curve in a post-lockdown world. Nature Human Behavior

Aburto, J. M., Kashyap, R., Scholey, J., Angus, C., Ermisch, J., Mills, M., & Dowd, J. B. (2020). Estimating the burden of COVID-19 on mortality, life expectancy and lifespan inequality in England and Wales: A population-level study. Journal of Epidemiology and Community Health.

Dowd, J. B., Andriano, L., Brazel, D. M., Rotondi, V., Block, P., Ding, X., & Mills, M. C. (2020). Reply to Nepomuceno et al.: A renewed call for detailed social and demographic COVID-19 data from all countries. Proceedings of the National Academy of Sciences

Dowd, J.B., Block, P., Rotondi, V. and Mills, M.C., (2020). Dangerous to claim “no clear association” between intergenerational relationships and COVID-19. Proceedings of the National Academy of Sciences

Dowd JB. The UK’s covid-19 data collection has been “world beating”—let’s not throw it away. BMJ. 2022 Feb 25;376.

Leininger, L.J., Albrecht, S.S., Buttenheim, A., Dowd, J.B., Ritter, A.Z., Simanek, A.M., Valentino, M.J. and Jones, M. (2022). Fight Like a Nerdy Girl: The Dear Pandemic Playbook for Combating Health Misinformation. American Journal of Health Promotion, 36(3), pp.563-567.

Alwan, N.A., Burgess, R.A., Ashworth, S., Beale, R., Bhadelia, N., Bogaert, D., Dowd, J., Eckerle, I., Goldman, L.R., Greenhalgh, T. and Gurdasani, D., (2020). Scientific consensus on the COVID-19 pandemic: we need to act now. The Lancet

Rose, N., Manning, N., Bentall, R., Bhui, K., Burgess, R., Carr, S., Cornish, F., Devakumar, D., Dowd, J.B., Ecks, S. and Faulkner, A., (2020). The social underpinnings of mental distress in the time of COVID-19–time for urgent action. Wellcome open research

Verhagen, M. D., Brazel, D. M., Dowd, JB., Kashnitsky, I., & Mills, M. (2020). Forecasting spatial, socioeconomic and demographic variation in COVID-19 health care demand in England and Wales. BMC Medicine

Gaye, B., Khoury, S., Cene, C.W., Kingue, S., N’Guetta, R., Lassale, C., Baldé, D., Diop, I.B., Dowd, J.B., Mills, M.C. and Jouven, X., (2020). Socio-demographic and epidemiological consideration of Africa’s COVID-19 response: what is the possible pandemic course? Nature Medicine

Rotondi, V, Andriano L, Dowd JB & Mills MC. (2020). Early evidence that social distancing and public health interventions flattened the COVID-19 curve in Italy. OSF Preprint

Ritter, A.Z., Aronowitz, S., Leininger, L., Jones, M., Dowd, J.B., Albrecht, S., Buttenheim, A.M., Simanek, A.M., Hale, L. and Kumar, A.,(2021). Dear Pandemic: Nurses as key partners in fighting the COVID‐19 infodemic. Public Health Nursing.


The human microbiome:

Mirzayi, C.A., Renson, A., Zohra, F., Elsafoury, S., Kasselman, L., van de Wijgert, J.H., Segata, N., Beghini, F., Eckenrode, K., Dowd, J.B. and Jones, H., (2021). Reporting guidelines for human microbiome research, the STORMS checklist. Nature Medicine.

Geistlinger, L., Mirzayi, C., Zohra, F., Azhar, R., Elsafoury, S., Grieve, C., ... & Waldron, L. (2022). BugSigDB: accelerating microbiome research through systematic comparison to published microbial signatures. medRxiv.

Renson, A., Kasselman, L.J., Dowd, J.B., Waldron, L., Jones, H.E. and Herd, P., (2020). Gut bacterial taxonomic abundances vary with cognition, personality, and mood in the Wisconsin Longitudinal Study. Brain, Behavior, & Immunity-Health

Renson, A., Mullan Harris, K., Dowd, J. B., Gaydosh, L., McQueen, M. B., Krauter, K. S., ... & Aiello, A. E. (2020). Early signs of gut microbiome aging: biomarkers of inflammation, metabolism, and macromolecular damage in young adulthood. The Journals of Gerontology: Series A.

Renson A, Herd P, Dowd JB (2019). Sick Individuals and Sick (Microbial) Populations: Challenges in Epidemiology and the Microbiome. Annual Reviews of Public Health

Bowyer, RCE, Jackson MA, Le Roy C, Lochlainn MN, Spector TJ. (2020), Socioeconomic Status and the Gut Microbiome: a TwinsUK Cohort Study, Microorganisms 

Herd, P, Palloni A, Rey F, Dowd JB (2018). Social and population health science approaches to understand the human microbiome. Nature Human Behavior

Dowd, JB and Renson A. (2018). “Under the Skin” and into the Gut: Social Epidemiology of the Microbiome, Current Epidemiological Reviews

Schiffer L, Rimsha A, Shephard L, Ramos M, Geistlinger L, Hutternhower C, Dowd JB, Segata N, Waldron L. (2019). HMP16SData: Efficient Access to the Human Microbiome Project through Bioconductor, American Journal of Epidemiology

Renson, A., Jones, H.E., Beghini, F., Segata, N., Zolnik, C.P., Usyk, M., Moody, T.U., Thorpe, L., Burk, R., Waldron, L. and Dowd, J.B., (2019). Sociodemographic variation in the oral microbiome. Annals of epidemiology

Pasolli, E., Schiffer, L., Manghi, P., Renson, A., Obenchain, V., Truong, D.T., Beghini, F., Malik, F., Ramos, M., Dowd, J.B. and Huttenhower, C., (2017). Accessible, curated metagenomic data through ExperimentHub. Nature methods

Rosenbaum, J., Usyk, M., Chen, Z., Zolnik, C.P., Jones, H.E., Waldron, L., Dowd, J.B., Thorpe, L.E. and Burk, R.D., (2019). Evaluation of oral cavity DNA extraction methods on bacterial and fungal microbiota. Scientific reports

Beghini, F., Renson, A., Zolnik, C.P., Geistlinger, L., Usyk, M., Moody, T.U., Thorpe, L., Dowd, J.B., Burk, R., Segata, N. and Jones, H.E., (2019). Tobacco exposure associated with oral microbiota oxygen utilization in the New York City Health and Nutrition Examination Study. Annals of epidemiology


Social determinants, biomarkers, infections & immune function:

Noppert, Grace A., Rebecca C. Stebbins, Jennifer Beam Dowd, and Allison E. Aiello (2023). Sociodemographic Differences in Population-Level Immunosenescence in Older Age. Brain, Behavior, and Immunity

Noppert, G.A., Feinstein, L., Dowd, J.B., Stebbins, R.C., Zang, E., Needham, B.L., Meier, H.C., Simanek, A. and Aiello, A.E., (2020). Pathogen burden and leukocyte telomere length in the United States. Immunity & Ageing, 17(1), pp.1-10.

Stebbins, R.C., Noppert, G.A., Yang, Y.C., Dowd, J.B., Simanek, A. and Aiello, A.E., (2020). Immune Response to Cytomegalovirus and Cognition in the Health and Retirement Study. American Journal of Epidemiology.

Noppert, G.A., Stebbins, R.C., Dowd, J.B., Hummer, R.A. and Aiello, A.E., (2020). Life Course Socioeconomic Disadvantage and the Aging Immune System: Findings from the Health and Retirement Study. The Journals of Gerontology: Series B

Hayward S, Dowd JB, Fletcher HA, Nellums L, Wurie F, Boccia D (2019). A systematic review of the impact of psychosocial factors on immunity: implications for enhancing BCG response against tuberculosis. Social Science and Medicine-Population Health

Courtin, E, Nafilyan V, Avendano M, Meneton P, Berkman L, Goldberg M, Zins M, Dowd JB (2018). Longer schooling but no better off? A quasi-experimental study of the effect of compulsory schooling on biomarkers in France. Social Science and Medicine

Steptoe, A, Hiltl TJ, Dowd JB, Hamer M (2018). Socioeconomic status and central adiposity as determinants of stress-related biological responses relevant to cardiovascular disease risk. Brain, Behavior, and Immunity

Herd, P., Mills, M. C., & Dowd, J. B. (2021). Reconstructing sociogenomics research: Dismantling biological race and genetic essentialism narratives. Journal of Health and Social Behavior, 62(3), 419-435.

Simanek, A.M., Parry, A. and Dowd, J.B., (2018). Differences in the association between persistent pathogens and mood disorders among young-to middle-aged women and men in the US. Brain, behavior, and immunity

Dowd, J.B., Bosch, J.A., Steptoe, A., Jayabalasingham, B., Lin, J., Yolken, R. and Aiello, A.E., (2017). Persistent herpesvirus infections and telomere attrition over 3 years in the Whitehall II cohort. The Journal of infectious diseases

Meier, H.C., Haan, M.N., de Leon, C.F.M., Simanek, A.M., Dowd, J.B. and Aiello, A.E., (2016). Early life socioeconomic position and immune response to persistent infections among elderly Latinos. Social Science & Medicine

Aiello, A.E., Feinstein, L., Dowd, J.B., Pawelec, G., Derhovanessian, E., Galea, S., Uddin, M., Wildman, D.E. and Simanek, A.M., (2016). Income and markers of immunological cellular aging. Psychosomatic medicine

Aiello, A.E., Dowd, J.B., Jayabalasingham, B., Feinstein, L., Uddin, M., Simanek, A.M., Cheng, C.K., Galea, S., Wildman, D.E., Koenen, K. and Pawelec, G., (2016). PTSD is associated with an increase in aged T cell phenotypes in adults living in Detroit. Psychoneuroendocrinology

Dowd, JB, Palermo T, Chyu L, Adam E, McDade TW (2014). Race/ethnic and socioeconomic differences in stress and immune function in the National Longitudinal Study of Adolescent Health (2014), Social Science and Medicine


Population Morbidity and Mortality:

Angus, C., Buckley, C., Tilstra, A. M., & Dowd, J. B. (2023). Increases in ‘Deaths of Despair’ during the COVID-19 pandemic in the United States and the United Kingdom. Public health, 218, 92-96.

Pongiglione, B., Ploubidis, G. B., & Dowd, J. B. (2022). Older Adults in the United States Have Worse Cardiometabolic Health Compared to England. The Journals of Gerontology: Series B, 77(Supplement_2), S167-S176.

Courtin, E, Dowd JB, Avendano M (2018). The Mental Health Benefits of Acquiring a Home in Older Age: A Fixed-Effects Analysis of Older Americans,  American Journal of Epidemiology

Chang, VW, Alley DE, Dowd JB (2017). Trends in the Relationship of Obesity and Disability, 1988-2012, American Journal of Epidemiology

Zajacova, A, Dowd JB, Schoeni RF, Wallace R (2015). Employment and income losses among cancer survivors: Estimates from a national longitudinal survey of American families. Cancer

Dowd, JB and Hamoudi A (2014). Life Expectancy and Education, American Journal of Public Health

Dowd, JB and Hamoudi A (2014). Is life expectancy really falling for low SES groups? Lagged selection bias and artifactual trends in mortality, International Journal of Epidemiology

Dowd, J. B., Angus, C., Zajacova, A., & Tilstra, A. (2022). Mid-life 'Deaths of Despair' Trends in the US, Canada, and UK, 2001-2019: Is the US an Anomaly?. medRxiv.

Tilstra, A. M., Aburto, J. M., Gutin, I., & Dowd, J. B. (2022). Coding of Obesity-related Mortality Impacts Estimates of Obesity on US Life Expectancy. medRxiv.

Dowd, JB and Zajacova A (2014). Long-term obesity and physical functioning in older Americans, International Journal of Obesity

Dowd, J.B. and Zajacova, A., (2014). Long-term obesity and cardiovascular, inflammatory, and metabolic risk in US adults. American journal of preventive medicine

Hamoudi, A. and Dowd, J.B., (2014). Housing wealth, psychological well-being, and cognitive functioning of older Americans. Journals of Gerontology Series B: Psychological Sciences and Social Sciences, 69(2), pp.253-262.


For a full list of publications:

 

Recent highlights

New paper in Nature Human Behaviour on Life Expectancy drops since COVID-19

Read Jenn’s summary of the paper in The Conversation